硕士导师

姓名:程晓非

职称:

学科领域:

研究方向:lqs

邮箱:

个人简历

学习经历:

2000.09-2004.07:安徽大学生物科学专业,理学学士;

2004.09-2007.06:云南农业大学植物病理专业,农学硕士;

2007.09-2010.07:浙江大学生物化学与分子生物学,理学博士;

2008.08-2009.07:美国Noble Foundation,国家留学基金委员公派博士。

作经历:

2010.08-2013.09,杭州师范大学生命与环境科学学院,助理研究员;

2013.10-2017.10,杭州师范大学生命与环境科学学院,副研究员;

2013.09-2016.09,加拿大农业部伦敦研究和发展中心,NSERC博后;

2016.10-2017.02,加拿大农业部伦敦研究和发展中心,研究科学家;

2017.10-2022.11,东北农业大学农学院,教授;

2022.12-至今,东北农业大学植物保护学院,教授。

教学工作

授课情况:

本科生课程:《分子生物学》《农业微生物学》

研究生课程:《分子生物学实验技术》《SCI科技论文写作》

参编教材:

《植物病原病毒学》(第二版),参编,中国农业出版社,2022

教学获奖:

1.第二届金陵青年论坛一等奖,中国作物学会人才培养专业委员会,2022

2.第十一届青年教师教学技能大赛三等奖第一名,东北农业大学,2019

3.第4届青年教师教学技能大赛一等奖第一名,东北农业大学农学院,2018

科研工作

科研项目:

1.“植物病毒学”国家自然科学基金优秀青年基金(32022071),2021.1-2023.12,主持人,120万

2.“耐盐碱、抗旱大豆生物育种创新团队”黑龙江省自然科学基金创新研究团队(TD2022C003),骨干成员,100万

3.“植物与病原微生物互作”东北农业大学双一流学科建设经费,2021.01-2025.12,主持人,150万元

4.“苜蓿花叶病毒对大豆的致病机制及大豆抗性资源挖掘研究”中央支持地方高校改革发展资金人才培养支持计划项目,2019.12-2021.12,主持人,100万

5.“马铃薯X病毒编码的TGB2蛋白耦合病毒复制和运动的分子机理研究”国家自然科学基金面上项目(31671998),2017.01-2020.12,主持人,60万

6.“植物病毒抑制寄主系统性获得免疫的分子机理研究”黑龙江省自然科学基金重点项目(ZD2018002),主持人,20万

7.“大豆花叶病毒致病性差异的分子机制研究”黑龙江省留学回国人员择优资助项目启动类(2018QD0002),主持人,5万

8.“东农学者学术骨干启动基金“东北农业大学,主持人,50万

9.“利用人工锌指蛋白进行多价抗双生病毒的研究“国家自然科学基金青年基金(31101417),2012.1-2014.12,主持人,23万

10.“基于人工锌指核酸酶抗双生病毒体系的建立与评价”浙江省自然科学基金一般项目(Y3110175),2011.1-2013.12,主持人,8万

11.“抗双生病毒的人工锌指核酸酶的设计与筛选”杭州师范大学人才启动基金(2351001020),2011.1-2012.12,主持人,5万

论文著作

1.Yong Li, Xinlei Liu, Wenjia Deng, Jiahui Liu, Yue Fang, Ye Liu, Tingshuai, Ma, Ying Zhang, Yongguo Xue, Xiaofei Tang, Dan Cao, Zhifei Zhu, Xiaoyan Luan*,Xiaofei Cheng*. Fine mapping the soybean mosaic virus resistance gene in soybean cultivar Heinong 84 and development of CAPS markers for rapid identification. Viruses, 2022, 14, 2533.(中科院三区,5.818)

2.Siqi Yang, Ye Liu, Xiaoyun Wu,Xiaofei Cheng*, Xiaoxia Wu*. Synonymous codon pattern of cowpea mild mottle virus sheds light on its host adaptation and genome evolution. Pathogens, 2022, 11(4): 419.(中科院三区,4.531)

3.Xue Jiang, Yameng Luan, Mengzhu Chai, Yingshuai Yang, Yuting Wang,Wenjia Deng, Yonggang Li,Xiaofei Cheng*, Xiaoyun Wu*. The N-terminal α-helix of potato virus X-encoded RNA-dependent RNA polymerase is required for membrane association and multimerization. Viruses, 2022, 14: 1907.(中科院三区,5.818)

4.Xiaoyun Wu, Mengzhu Chai, Jiahui Liu, Xue Jiang, Yingshuai Yang, Yushuang Guo, Yong Li*,Xiaofei Cheng*. Turnip mosaic virus manipulates DRM2 expression to regulate host CHH and CHG methylation for robust infection. Stress Biology, 2022, 2: 29.

5.Yameng Luan, Lili Zhang, Ting Sun, Xue Jiang, Xiaoyun Wu,Xiaofei Cheng*. First report of a secovirus associated with mountain celery chlorotic spot disease in Heilongjiang, China. Plant Disease, 2021, 106:1331.(中科院二区,4.614)

6.Xiu Su, Xiang Zhou, Yuan Li, Liangjin Ma,Xiaofei Cheng*, Kai Guo*. First report of bean common mosaic virus infecting heavenly bamboo (Nandina demostica) in China. Plant Disease, 2021, 106: 1079.(中科院二区,4.614)

7.Jiahui Liu, Ye Liu, Yue Fang, Lili Zhang, Kaixin Yu, Xiaoyun Wu,Xiaofei Cheng*. Evaluation of potato virus X resistance in potato cultivars and identification of an innate immunity-independent resistance phenotype. Phytopathology Research, 2021, 3:21.(中科院二区,3.955)

8.孙婷,王馨玥,刘洪义,程晓非,武晓云.马铃薯奥古巴花叶病毒RT-PCR检测方法的建立及应用.植物检疫,2021,35(3):47-52.

9.Qi Li, Ningkun Liu, Qing Liu, Xingguo Zheng, Lu Lu, Wenrui Gao, Yang Liu, Yan Liu, Shicheng Zhang, Qian Wang, Jing Pan, Chen Chen, Yingjie Mi, Meiling Yang,Xiaofei Cheng, Guodong Ren, Yaowu Yuan, Xiaoming Zhang. DEAD-box helicases modulate dicing body formation in Arabidopsis. Science Advance, 2021, 7(18): eabc6266.

10.Xiaoyun Wu,Xiaofei Cheng*. Intercellular movement of plant RNA viruses: Targeting replication complexes to the plasmodesma for both accuracy and efficiency. Traffic, 2020, 21:725-736.(中科院二区,6.144)

11.Xinyang Che, Xue Jiang, Xinlei Liu, Xiaoyan Luan, Qi Liu,Xiaofei Cheng*, Xiaoyun Wu*. First report of Alfalfa mosaic virus on soybean in Heilongjiang, China. Plant Disease, 2020, 104 (11): 3085.(中科院二区,3.955)

12.Xiaoyun Wu, Jiahui Liu,Xiaofei Cheng*. First report of Camellia japonica associated emaravirus 1 associated with camellia leaf ringspot and flower color-breaking disease in China. Plant Disease, 2020, 104(12): 3271.(中科院二区,3.955)

13.Mengzhu Chai, Xiaoyun Wu, Jiahui Liu, Yue Fang, Yameng Luan, Xiaoyan Cui, Xueping Zhou, Aiming Wang,Xiaofei Cheng*. P3N-PIPO interacts with P3 via the shared N-terminal domain to recruit viral replication vesicles for cell-to-cell movement. Journal of Virology, 2020, 94(8): e01898-19. (热点论文)(中科院二区,6.549)

14.Md. Siddiqur Rahman, Xiaoxia Su, Kuanyu Zheng,Xiaofei Cheng, Ting Li, Lihua Zhao, Jiahong Dong, Zhongkai Zhang*. Characterization of a new isolate of Chilli ringspot virus in Yunnan,China. Journal of Crop Science and Biotechnology, 2020, 23: 57-63.

15.Ruonan Zhang, Xiaoyun Wu, Xue Jiang, Xiaoxia Wu, Xiaoyan Luan,Xiaofei Cheng*. Molecular characterization of Common bean curly stunt virus: a novel recombinant geminivirus in China. Archives of Virology, 2020, 165: 257-260.(中科院四区,2.685)

16.刘佳慧,刘野,张若男,武晓云,刘琦,程晓非*.山茶褪绿矮缩伴随病毒杭州分离物的序列和进化分析.植物病理学报,2020,50(1):117-121.

17.Jiahui Liu, Lili Zhang, Feifei Xu, Mengzhu Chai, Xiaodong Wu, Unsong Kim, Dianqiu Lv, Xiaoyun Wu, Xiaoxia Wu,Xiaofei Cheng*. Molecular analysis of a divergent isolate of potato virus H from potato reveals novel evolutionary feature of Carlaviruses. Canadian Journal of Plant Pathology, 2020, 42: 116-124.(中科院四区,2.074)

18.Xiaoyun Wu, Adrian Valli, Juan Antonio Garcia, Xueping Zhou,Xiaofei Cheng*. The tug-of-war between plants and viruses: great progress and many remaining questions. Viruses, 2019, 11: 203.(中科院三区,5.818)

19.Xiaoyun Wu+, Jiahui Liu+, Mengzhu Chai, Jinhui Wang, Dalong Li, Aiming Wang,Xiaofei Cheng*. The potato virus X TGBp2 protein plays dual functional roles in viral replication and movement. Journal of Virology, 2019, 93: e01635-18.(中科院二区,6.549)

20.Tong Han, Qiushi Hou,Xiaofei Cheng, Juan Antonio Garcia, Adrian Valli, Song Zhang, Mengji Cao, Caixia Yang. Complete genome sequence of a novel member of the family Potyviridae isolated fromPhellodendron amurenseRupr. in Liaoning, China. Archives of Virology, 2019, 164: 1705–1709.(中科院四区,2.685)

21.Xiaoyun Wu, Qi Liu, Mengzhu Chai, Lili Zhang,Xiaofei Cheng*, First report of Potato aucuba mosaic virus on potato in China. Plant Disease, 2018 102(12): 2671.(中科院二区,3.955)

22.Xiaodong Wu, Xiaoyun Wu, Wenbin Li,Xiaofei Cheng*. Molecular characterization of a divergent strain of calla lily chlorotic spot virus infecting celtuce (Lactuca sativavar. augustana) in China. Archives of Virology, 2018, 163(5): 1375-1378.(中科院四区,2.685)

23.Xiaodong Wu,Xiaofei Cheng*, Wenbin Li*. First report of natural infection of Watermelon mosaic virus onLagerstroemia indicain China. Plant Disease, 2018, 102(5): 1048.(中科院二区,3.955)

24.Xiaofei Cheng+,RuyiXiong+,YinziLi,FangfangLi,XuepingZhou,AimingWang*. Sumoylation of theturnip mosaic virus RNA polymerase promotes viral infection by counteracting the host NPR1-mediated immune response. Plant Cell, 2017, 29(3): 508-525.(中科院一区,12.085)

25.Xiaofei Cheng,AimingWang*. The potyviral silencing suppressor protein VPg mediates degradation of SGS3 via ubiquitination and autophagy pathways. Journal of Virology, 2017, 91(1): e01478-16.(中科院二区,6.549)

26.Xiaofei Cheng, Aiming Wang*. Multifaceted defense and counter-Defense in co-evolutionary arms race between plants and viruses. Communicative & Integrative Biology, 2017, 10:4, e1341025.

27.Yushuang Guo, Mengao Jia, Yuemei Yang, Linlin Zhan,Xiaofei Cheng, Jianyu Cai, Jie Zhang, Jie Yang, Tao Liu, Qiang Fu, Jiehong Zhao, Imran Haider Shamsi. Integrated analysis of tobacco miRNA and mRNA expression profiles under PVY infection provides insight into tobacco-PVY interactions. Scientific reports, 2017, 7: 4895.(中科院三区,4.996)

28.LingyunChen,Xiaofei Cheng,JianyuCai,LinlinZhan,XiaoxiaWu,QiLiu, XiaoyunWu*. Multiple virus resistance using artificial trans-acting siRNAs. Journal of Virological Methods, 2016, 228: 16-20.(中科院四区,2.623)

29.Zhiling Wang, Zhao Z,Xiaofei Cheng, Suqi Liu, Qin Wei, Ian M. Scott. Conifer flavonoid compounds inhibit detoxification enzymes and synergize insecticides. Pesticide biochemistry and physiology, 2016, 127:1-7.(中科院一区,4.966)

30.Xiaofei Cheng,PingDeng,HongguangCui,AimingWang*. Visualizing double-stranded RNA distribution and dynamics in living cells by dsRNA binding-dependent fluorescence complementation. Virology, 2015, 485: 439-451. (封面论文)(中科院三区,3.513)

31.Xiaofei Cheng*, FangfangLi,JianyuCai,WeiChen,NanZhao,YuqiangSun,YushuangGuo,XiulingYang,XiaoyunWu*. Artificial TALE as a convenient protein platform for engineering broad-spectrum resistance to begomoviruses. Viruses, 2015, 7: 4772-4782.(中科院三区,5.818)

32.YilunWang+,XiaofeiCheng+,XiaoxiaWu,AimingWang,XiaoyunWu*. Characterization of complete genome and small RNA profile of pagoda yellow mosaic associated virus, a novel badnavirus in China. Virus Research, 2014, 188: 103-108.(中科院三区,6.286)

33.WeiChen,YongshengQian,XiaoyunWu,YuqiangSun,XiaoxiaWu,XiaofeiCheng*. Inhibiting replication of begomoviruses using artificial zinc finger nucleases that target viral-conserved nucleotide motif. Virus Genes, 2014, 48:494–501.(中科院四区,2.198)

34.XiaofeiCheng*,NasarVirk,WeiChen,ShuqinJi,ShuxianJi,YuqiangSun,XiaoyunWu*. CpG usage in RNA viruses: data and hypotheses. Plos One, 2013, 8(9): e74109.(中科院三区,3.752)

35.XiaofeiCheng,WeiChen,ZhenhuaZhou,JunjunLiu,HuizhongWang*. Functional characterization of a novel tropinone reductase-like gene inDendrobium nobileLindl. Journal of Plant Physiology, 2013, 170: 958-964.(中科院三区,3.686)

36.WeiChen+,XiaofeiCheng+,ZhenhuaZhou,JunjunLiu,HuizhongWang*. Molecular cloning and characterization of a tropinone reductase fromDendrobium nobileLindl. Molecular Biology Reports, 2013, 40: 1145-1154.(中科院四区,2.742)

37.XiaofeiCheng*,XiaoyunWu,HuizhongWang,YuqiangSun,YongshengQian,LuLuo. High codon adaptation in citrus tristeza virus to its citrus host. Virology Journal, 2012, 9: 113.(中科院三区,5.913)

38.XiaoyunWu,HaitaoDing,LipingKe,YueyongXin,XiaofeiCheng* Characterization of an acid-resistant glucose 1-dehydrogenase fromBacillus cereusvar. mycoides, Romanian Biotechnological Letters, 2012, 17(4): 7540-7548.

39.XiaofeiCheng,XiaoqiangWang,JianxiangWu,Rob WBriddon,XuepingZhou*.βC1 encoded by tomato yellow leaf curl China betasatellite forms multimeric complexes in vitro and in vivo. Virology, 2011, 409: 156-162.(中科院三区,3.513)

40.XiaofeiCheng,JunpingWu,XinyinMa,HuafuFu,XiaoyunWu. First report of citrus tristeza virus inCitrus changshanensiscv. Huyou in Zhejiang, China. Journal of plant Pathology, 2011, 93(s4): 68. IF=1.043;(中科院四区,1.217)

41.XiaoyunWu,JianxiangWu,XiaofeiCheng*. First report of natural infection of broad bean wilt virus-2 onLactuca indica. Journal of Plant Pathology, 2010, 92(s4): 119.(中科院四区,1.217)

42.XiaofeiCheng,JiahongDong,QiFang,MingDing,JeniferMcBeatch, ZhongkaiZhang. Detection of impatiens necrotic spot virus infectingPhalaenopsisin Yunnan. Journal of Plant Pathology, 2010, 92(2): 545.(中科院四区,1.217)

43.JiahongDong+,XiaofeiCheng+,YueyanYin,QiFang,MingDing,TingtingLi,LizhenZhang,XiaoxiaSu,JeniferMcBeath,ZhongkaiZhang. Characterization of tomato zonate spot virus, a new tospovirus species in China. Archives of Virology, 2008, 153(5): 855-864.(中科院四区,2.685)

44.Wenfeng Fu, Ying Shen, Juan Hao, Jianyong Wu, Liping KeP,Caiyun Wu, Kai Huang, Binglun Luo, Mingfeng Xu,Xiaofei Cheng, Xueping Zhou, Jie Sun, Chaozhu Xing, Yuqiang Sun. Acyl-CoA N-acyltransferase influences fertility by regulating lipid metabolism and jasmonic acid biogenesis in cotton. Scientific Reports, 2015, 5: 11790.(中科院三区,4.996)

45.LipingKe,Rui’eLiu,BijueChu,XiushuangYu,JieSun,BrianJones,GangPan,XiaofeiCheng,HuizhongWang,ShujinZhu,YuqiangSun. Cell suspension culture-mediated incorporation of the rice Bel gene into transgenic cotton. PLoS One, 2012, 7(7): e39974.(中科院三区,3.752)

46.Xiaoyun Wu,Xiaofei Cheng, Lu Luo, Xiaoxia Wu. Genetic diversity and global distribution of citrus tristeza virus (CTV) strains. Journal of Northeast Agricultural University (English Edition), 2012, 19:9-18.

47.尹跃燕,董家红,程晓非,李婷婷,丁铭,方琦,张仲凯.番茄环纹斑点病毒核壳体蛋白抗血清制备及其血清学特性分析.植物病理学报, 2011, 41: 482-485.

48.程晓非,董家红,方琦,李婷婷,丁铭,张仲凯.从云南蝴蝶兰上检测到番茄斑萎病毒属病毒.植物病理学报,2008,38(1):31-34.

49.程晓非,张仲凯,李正跃.西花蓟马(Frankliniella occidentalis)rDNA ITS2和COⅠ基因5´末端序列的克隆及分析.浙江大学学报(农业与生命科学版),2009,35(4):355-364.

科研成果

专利:

1.授权发明专利:一种苜蓿花叶病毒的侵染性克隆、重组农杆菌及构建方法(排名第1),2022-01-11,中国ZL202010461785.8。

2.授权发明专利:一种马铃薯X病毒弱毒疫苗及其制备方法与应用(排名第1),2021-12-21,中国,ZL201811376177.6。

获奖:

1.中国农学会青年科技奖(排名第1),2022

2.黑龙江省委教育工委优秀共产党员(排名第1)2021

3.东北农业大学突出贡献奖(排名第1)2021

4.东北农业大学五四青年奖章(排名第1),2020

5.NSERC Fellowship Award(排名第1),2013

社会兼职

期刊编委:Virology、Frontiers in Genetics、Frontiers in Microbiology

学会理事:中国植物病毒学会植物与病原互作专业委员会理事,中国作物学会马铃薯专业委员会理事,第三届黑龙江省青年科技工作者协会理事农业科技界别主任、东北农业大学第八届教授委员会委员、